Can Hallucinogens Cause Flashbacks?

Medically Reviewed:
Dr. Randy Gelow, MD, FASAM
Ray Hamilton, DNP, PMHNP-BC, FNP-C
Last Updated: July 15, 2025

Hallucinogenic drugs have long intrigued scientists and users alike for their ability to alter visual perception and consciousness. However, these drugs carry risks, including persistent side effects such as flashbacks and a rare but serious medical condition known as Hallucinogen Persisting Perception Disorder (HPPD).

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Hallucinogens Explained

Hallucinogenic drugs, also known as hallucinogens, are substances that alter a person’s perception of reality. They can cause users to see, hear, or feel things that aren’t really there — these effects are called hallucinations. These drugs affect the brain’s chemistry and can lead to changes in mood, thoughts, and sensory perception.

Most hallucinogens affect neurotransmitters like serotonin and glutamate. These changes in brain chemicals disrupt communication between brain regions, leading to altered perception, mood swings, and a distorted sense of time and space.

Types of Hallucinogenic Drugs

Hallucinogens are typically divided into two categories:

1. Classic Hallucinogens

These affect serotonin levels in the brain and often lead to visual and sensory distortions. Examples include:

  • LSD (lysergic acid diethylamide)
  • Psilocybin (found in magic mushrooms)
  • Mescaline (found in peyote cactus)
  • DMT (dimethyltryptamine)

2. Dissociative Drugs

These can cause a feeling of detachment from one’s body or surroundings. They often affect glutamate, a brain chemical involved in learning and memory. Examples include:

  • Ketamine
  • PCP (phencyclidine)
  • DXM (dextromethorphan) – found in some cough syrups

Can Hallucinogens Cause Flashbacks?

Yes, hallucinogenic drugs such as LSD, psilocybin mushrooms, and mescaline can cause flashbacks occurring days or even months after the initial drug use. These flashbacks are spontaneous episodes where a person briefly re-experiences distortions or visual phenomena similar to those they had while actively under the influence.

Flashbacks are typically short-lived and include flashes of color, geometric patterns, or halos around objects. Although these episodes can be unsettling, they are often harmless and resolve on their own. However, in some cases, flashbacks can be distressing or frequent enough to disrupt daily life, leading to a clinical diagnosis known as Hallucinogen Persisting Perception Disorder (HPPD).

What Do Flashbacks Feel Like?

Flashbacks often involve changes in a person’s visual perception. Common experiences include:

  • Seeing flashes of color or bright lights
  • Visual trails following moving objects
  • Halos or auras around stationary objects
  • Distortions in size where objects may appear larger or smaller

These episodes can occur unexpectedly. Many people report being triggered by stress, fatigue, or exposure to other substances. Emotionally, flashbacks can vary widely. Some people feel neutral or mildly fascinated, while others feel anxiety or fear.

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Understanding Hallucinogen Persisting Perception Disorder (HPPD)

Hallucinogen Persisting Perception Disorder is a rare medical condition where visual symptoms persist long after hallucinogenic drug use has ended. This disorder is recognized by the American Psychiatric Association in the DSM-IV-TR and DSM-5.

HPPD is different from occasional flashbacks in its persistence and intensity. While many users experience occasional flashbacks, cases of HPPD involve ongoing visual phenomena that interfere with daily life. There are two types of HPPD:

  • Type 1 HPPD: Characterized by brief, intermittent flashbacks.
  • Type 2 HPPD: A chronic form featuring continuous or very frequent visual disturbances lasting months or years.

Though most well-known in connection with LSD use, some reports also show a relationship of this condition with other hallucinogenic drugs such as cannabis and MDMA. Notably, people with HPPD sometimes develop symptoms after just one use of the drug.

HPPD Symptoms

The symptoms of HPPD are primarily visual symptoms and include:

  • Visual snow or static across the visual field
  • Trails or afterimages (palinopsia) when looking away from moving objects
  • Halos or auras surrounding lights or objects
  • Changes in size perception such as micropsia (objects appear smaller) or macropsia (objects appear larger)
  • Intensified colors or light flashes
  • Difficulty focusing or distorted motion perception

These symptoms reflect a disruption in normal visual perception. For many, they cause distress and can impair concentration, reading, or driving.

How Long Does HPPD Last?

The duration of HPPD varies greatly between individuals. In some reported case reports, symptoms have resolved within weeks or months. However, other HPPD patients experience persistent long-term symptoms that last for years, leading to chronic impairment.

Factors that influence how long HPPD lasts include:

  • Frequency and dosage of hallucinogen use
  • Type of drug used
  • Individual susceptibility and neurological differences

 

Because of this variability, no clear timeline exists. Some people recover spontaneously, while others require treatment to manage symptoms.

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Is There a Standard HPPD Treatment?

Currently, no standardized treatment cures HPPD. Education and reassurance may reduce anxiety about symptoms. Several approaches also help manage symptoms:

  • Avoiding triggers such as stress or additional substance use.
  • Psychotherapy can assist with coping, especially if symptoms cause anxiety or depression.
  • Some HPPD patients benefit from medications such as benzodiazepines or selective serotonin reuptake inhibitors (SSRIs), although results vary, and SSRIs may worsen symptoms in some cases.
  • Experimental treatments include clonidine and other drugs targeting the nervous system’s visual pathways.

It’s important for anyone developing persistent symptoms post drug use to consult a healthcare professional familiar with HPPD.

Why Understanding HPPD Matters

HPPD remains a poorly understood but impactful medical condition. Understanding its symptoms and causes ensures better diagnosis and reduces stigma for affected individuals.

Because the use of hallucinogenic drugs is increasing in medical and recreational contexts, awareness of long-term side effects is essential. Early recognition can guide better treatment and improve outcomes.

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Seeking Help for Hallucinogen Addiction

While many hallucinogenic drugs are not considered as addictive as substances like opioids or alcohol, some people can develop hallucinogen addiction, especially with repeated use of certain drugs like PCP or high doses of MDMA.

If you or a loved one is experiencing persistent visual symptoms, flashbacks, or finds themselves unable to stop using hallucinogens despite negative consequences, professional help is crucial. Treatment often includes:

  • Behavioral therapies, such as cognitive-behavioral therapy (CBT) to address thought patterns and reduce drug use
  • Counseling and peer support groups provide social support and coping strategies
  • Medical supervision to manage withdrawal and co-occurring mental health conditions, such as post-traumatic stress disorder (PTSD)

If you are concerned about addiction or long-term side effects from hallucinogenic drugs, reaching out to a healthcare professional or a trusted addiction treatment center is the first step toward recovery and regaining control over your health and life.

Early intervention improves outcomes and helps prevent worsening of persisting perception disorder HPPD or other complications.Our addiction and detox facilities in Scottsdale, Arizona, are open 24/7 to provide support and treatment to those who are in need. Connect with our team today and begin your journey to a lasting recovery.

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